Ian D Hickson Selected Research

Neoplasms (Cancer)

1/2020	Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes.
1/2020	Tumour predisposition and cancer syndromes as models to study gene-environment interactions.
1/2020	Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase.
1/2019	The RIF1-PP1 Axis Controls Abscission Timing in Human Cells.
3/2018	Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism.
1/2018	Anaphase: a fortune-teller of genomic instability.
6/2017	Potential biomarkers of DNA replication stress in cancer.
12/2015	Replication stress activates DNA repair synthesis in mitosis.
4/2015	Regulation of SUMO2 target proteins by the proteasome in human cells exposed to replication stress.
1/2015	Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells.

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Ian D Hickson Research Topics

Disease

26	Bloom Syndrome 01/2018 - 04/2002
24	Neoplasms (Cancer) 01/2020 - 04/2002
21	Genomic Instability 12/2019 - 11/2002
9	Chromosomal Instability (Chromosome Stability) 01/2019 - 04/2002
4	Ataxia Telangiectasia (Louis Bar Syndrome) 02/2016 - 04/2002
4	Fanconi Anemia (Fanconi's Anemia) 10/2011 - 09/2005
3	Chromosome Aberrations (Chromosome Abnormalities) 01/2020 - 04/2002
3	Aneuploidy (Aneuploid) 12/2018 - 12/2015
3	Carcinogenesis 04/2015 - 09/2003
3	Werner Syndrome (Werner's Syndrome) 09/2005 - 04/2002
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2018 - 07/2016
2	Hypersensitivity (Allergy) 12/2015 - 09/2005
2	Premature Aging 09/2003 - 11/2002
1	Bites and Stings (Sting) 01/2022
1	Fragile X Syndrome (Martin Bell Syndrome) 12/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 07/2016
1	Myalgia 07/2016
1	Inborn Genetic Diseases (Disease, Hereditary) 09/2003
1	Leukemia 04/2003
1	Breast Neoplasms (Breast Cancer) 04/2002

Drug/Important Bio-Agent (IBA)

20	DNA (Deoxyribonucleic Acid)IBA 12/2019 - 04/2002
20	RecQ HelicasesIBA 05/2015 - 11/2002
15	Proteins (Proteins, Gene)FDA Link 01/2019 - 06/2002
5	DNA HelicasesIBA 06/2009 - 01/2005
4	Bloom syndrome proteinIBA 07/2014 - 03/2004
3	ChromatinIBA 01/2018 - 09/2005
2	trioctyl phosphine oxide (TOPO)IBA 12/2015 - 04/2003
2	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 10/2013 - 04/2002
2	Type I DNA Topoisomerases (Topoisomerase I)IBA 10/2005 - 11/2002
2	Cruciform DNA (Holliday Junctions)IBA 10/2005 - 05/2004
2	Staphylococcal Protein A (Protein A)IBA 10/2005 - 03/2004
1	Interferon Type IIBA 01/2022
1	InterferonsIBA 01/2022
1	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/2020
1	CarcinogensIBA 01/2020
1	CamptothecinIBA 01/2020
1	diazonaphthalenedisulfonic acid (NDS)IBA 01/2020
1	Indoleacetic Acids (Auxin)IBA 01/2020
1	Folic Acid (Vitamin M)FDA LinkGeneric 12/2018
1	Mitochondrial DNA (mtDNA)IBA 01/2018
1	A-Form DNA (A-DNA)IBA 11/2017
1	Biomarkers (Surrogate Marker)IBA 06/2017
1	CholesterolIBA 07/2016
1	Biological ProductsIBA 07/2016
1	Glucose (Dextrose)FDA LinkGeneric 07/2016
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 07/2016
1	Carrier Proteins (Binding Protein)IBA 02/2016
1	Type II DNA Topoisomerases (Topoisomerase II)IBA 12/2015
1	4,4'- (1,2- dimethyl- 1,2- ethanediyl)bis- 2,6- piperazinedioneIBA 12/2015
1	Messenger RNA (mRNA)IBA 07/2014
1	MicroRNAs (MicroRNA)IBA 07/2014
1	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2013
1	DNA Polymerase thetaIBA 04/2010
1	Small Interfering RNA (siRNA)IBA 04/2010
1	EnzymesIBA 06/2009
1	DNA Polymerase IIIIBA 09/2008
1	Protein Kinases (Protein Kinase)IBA 10/2005
1	Ataxia Telangiectasia Mutated ProteinsIBA 10/2005
1	DNA-Activated Protein KinaseIBA 10/2005
1	Cisplatin (Platino)FDA LinkGeneric 09/2005
1	Single-Stranded DNA (DNA, Single Stranded)IBA 01/2005
1	Chromatin Assembly Factor-1IBA 06/2004
1	EndonucleasesIBA 03/2004
1	Flap EndonucleasesIBA 03/2004
1	Exonucleases (3' 5' Exonuclease)IBA 03/2004
1	Phosphotransferases (Kinase)IBA 02/2004
1	Etoposide (VP 16)FDA LinkGeneric 04/2003
1	Telomere-Binding ProteinsIBA 10/2002

Therapy/Procedure

1	Therapeutics 06/2017
1	Radiotherapy 04/2010